All About Niacin Detox, Flush, THC Pills, Drug Test Dosage & Side Effects

What is niacin detox and how does it work? How fast does niacin clean your system? In this article, learn more about flush, how it works and whether or not it will help you pass a THC drug test. Also find out which niacin is the best for detox and dosage and the flush may help with weight loss and possible detox side effects.

Niacin Detox Flush

What is niacin?

Also called nicotinic acid or vitamin B3,  niacin is a water soluble  vitamin that occurs naturally in plants and animals. It is also present in vitamin and nutritional supplements.

Niacin Chemical Structure

As you may have learnt in your biology classes, the liver, as the primary detoxification or cleansing organ of your body. It neutralizes and gets rid of harmful substances in your body. Niacin is one of the major vitamins and minerals required by the liver to keep up the cleansing process.This b vitamin can release the toxins and heavy metals stored up in fat cells.


It is used to treat and prevent niacin deficiency and lower cholesterol and triglycerides in the blood.

How does Niacin flush Detox work?

Niacin detoxifies the body by opening up small blood vessels (capillaries),  and increasing blood flow. The opening of blood vessels is called vasodilation.

Capillaries are the closest to fat tissues. Toxins will usually build up in fatty tissues where larger vessels do not reach. Increased blood allows for the toxins to be processed and flushed out of the body.

How fast does Niacin Clean your System?

According to reviews from different online user platforms like Yahoo, niacin  may take from between 4 hours to a week for you to clean your system. some niacin detox kits take up to a month.

Some users say that they key for to work fast and  effectively is to  balance it with other vitamins  while taking plenty of water. Some  individuals recommend taking niacin a long with goldenseal-a herb that is also thought to detox your system. While within the working period be sure not take excess because it may lead to harmful effects as you will learn shortly.

How long does Niacin Flush Last

While niacin opens up blood vessels, it makes blood rush or flow quickly to the surface of the skin. It is a temporary reaction that makes the skin to appear warm and blushed. With increased blood flow the cells are also sensitized to release histamines.

This hormone signals the body to produce more blood. The increased presence of histamines may cause itching which is a common side effect of niacin detox programs.

Niacin flush before and after picture
Vitamin B3 Flush before and after

The flush occurs within 20 to 30 minutes after the vitamin has been taken and usually only lasts a few minutes. Blushed skin diminishes naturally the longer you take niacin.


Niacin THC Detox Pills

According to, THC is tetrahyrocannabiol, the chemical compound found in cannabis and it is responsible for most of marijuana’s psychological effects. THC is stored in the adipose tissue. While there is still no scientific evidence, high doses of niacin have been used to cleanse THC out of the blood. It aids the body to get rid of THC through the urinary tract.

It has been noted over the years that niacin THC detox is used in excess making it a controversial detox method. It is important to note that hepatotoxicity is rare but if taken over a long period of time niacin can cause liver injury- people with liver damage should not use niacin for THC detox.

It is important to note that taking high doses of niacin to flush out THC can be dangerous. It may lead to side effects such as flushing, itching and skin rashes. Adverse reactions that are associated with using a niacin THC detox include: nausea, vomiting, abdominal cramps and diarrhea.

Other than taking these supplements, to effectively flush out your body of THC, incorporate, proper diet and exercise into your program. Also, take lots of clean water to aid your body in flushing out toxins.

Note that niacinamide, another form of niacin should not be taken while on a detox program as it is designed to do the exact opposite by preventing vaso-dilation.

Niacin  Detox Drug Test-24 Hours?

Some people take niacin supplements in an effort to mask drug tests. It is important to note that even with lots of information on the internet that it works. Basing on expert opinion and other authentic resources, it cannot work. There is no scientific proof for this claim.

Niacin should by no means be used for instant detox. Using niacin detox to pass a drug test may not always work. Proper dosage should be taken to avoid any unpleasant effects.

It should be used up to 24 hours before a drug test. Within this period, you should not take any more drugs as this will increase the risk of failing the test. Note that, using it 24 hours before the tests does not mean it will always work. as mention earlier, it may take longer.

While some say that niacin helped them to pass a drug test, most people think that this is just a scam and it is no way a safe alternative.

According to, while there is a lot of information online that suggests niacin can be used to foil a drug test, there is no scientific evidence that indicates that taking niacin can help you to pass a urine drug test.

 Dosage -How much Niacin for Detox?

The recommended daily dietary intake of niacin is 14-16 mg. Due to the controversy surrounding niacin for detox, there are no standard doses of niacin for detox. While some recommend taking 500mg- 2500mg of niacin for detox, the CDC warns that taking large doses of niacin may lead to unwanted side effects. Most naturopaths recommend a starting dose of 50mg.

Niacin should not be taken on an empty stomach to avoid flushes. High doses of niacin should only be taken under close supervision.

Niacin Detox Pills

Niacin detox pills are available by prescription in 50mg- 500mg tablets or capsules. The recommended therapeutic daily dose is 100mg taken three times daily up to a maximum of 1000mg daily.

niacin pills
Vitamin b3 Pills

Niacin detox pills are available in two safe forms:

Immediate release where the niacin in each tablet is released immediately- it usually triggers a hot flush (a warm itchy feeling on the skin). When using these pills, it is best to start at a lower dose of 250mg and gradually increase the dose to achieve the desired amount. Immediate release niacin should not be taken more than twice a day.

Extended release niacin capsules are available at 125mg-1000mg and are usually taken in a dose of 500mg at bedtime up to a maximum of 2000mg per day. Side effects are commonly experienced with doses that exceed 1000mg per day.

Which is the Best?

Of the three, the best niacin for detox is the extended release type. Extended release is a time release niacin which unlike slow release is safe and rarely causes adverse effects. Extended release niacin supplements are best used with diet. These should however be avoided if you have liver problems, stomach ulcers or bleeding disorders.

GNC Niacin 500 mg Drug Test

What is the effectiveness of niacin 500 mg for drug test? GNC’s niacin 500mg is a dietary supplement, that in addition to vitamin b3 comes with other ingredients including, Cellulose, Whole Brown Rice Powder (Oryza sativa)
According to the manufacturer, it is free of sugar,artificial colors, artificial flavors, preservatives, sodium, wheat, gluten,soy, dairy and yeast.
It is one the most sought when it come to drug test but there is no solid evidence that it is the most effective. It is just a dietary supplement.

gnc niacin 500mg drug test
GNC Niacin


Does Flush Free Niacin work for Drug Test

When shopping for niacin supplements, you might have noticed flush free on the label. What does flush free mean on a niacin bottle?
The “flush” refers to the hot feeling and skin redness that results from taking a fair amount of the supplement. It is a common effect. Therefore, flush free means that you will not feel the hotness and redness.
Flush free niacin works for drug test just the same way as the regular niacin. Whether it works or not is based on hearsay.

Flush free Niacin
Flush free Niacin Brands


Niacin Detox Side Effects/Precautions

Some of the known side effects of niacin detox include;
Main Side effects that are not common that need immediate medical attention.

  • Severe stomach pain
  • Light gray-colored stools
  • Loss of appetite
  • Yellow eyes or skin
  • Darkening of urine
  • Abdominal or stomach pain

Minor side effects that often disappear with time thus do not need medical attention

  • Flushing or redness of the skin, especially on the
    face and neck
  • Cough
  • Diarrhea
  • Slight increase in body temperature
  • Headache
  • Nausea or vomiting
  • Rash or itching
  • Runny and or stuffy nose
  • Sneezing

In addition, niacin supplements are not recommended for patients with stomach ulcers or a history of liver disease. Niacin overdose can increase your risk of developing stomach ulcers and liver damage.
In terms interaction with other medications, it may interact with particular medications, including

  • Aspirin, Anticoagulants,
  • Diabetes medications
  • Nicotine patches

Be sure to consult your doctor before taking niacin supplements. At the same time you may experience a feeling of drowsiness if take niacin supplements while drinking alcohol

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